DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - AM-281

Collection D4 : TTD
Chemical Name AM-281 ( From PubChem : AM 281 )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
557.212 g/mol 1 6 5.0649 False(2/4)
Structure
InChI InChI=1S/C21H19Cl2IN4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-4-15(22)12-17(18)23)20(13)14-2-5-16(24)6-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
InChIKey AJFFBPZYXRNAIC-UHFFFAOYSA-N
Links

Gene (4 / 10)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCNR1Successful target
TTDInhibitorCNR2Clinical trial target
PubChem PotencyuM7.943CYP2C19-GI(Protien) :
PubChem NoneuMCYP2C19-GI(Protien) :
PubChem PotencyuM6.310CYP2C9-GI(Protien) :
PubChem NoneuMCYP2C9-GI(Protien) :
ChEMBLAC50nM7943.280CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM7943.300CYP2C19
-Target : CHEMBL3622
ChEMBLAC50nM6309.570CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM6309.600CYP2C9
-Target : CHEMBL3397
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).