Tan Lab | DSigDB

Gene Set: D4 : TTD - ALTENUSIN

Collection

D4 : TTD

Chemical Name

ALTENUSIN ( From PubChem : ALTENUSIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
290.268 g/mol	4	6	2.4856	True

Structure

InChI

InChI=1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20)

InChIKey

Links

Gene (16 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			MCL1		Clinical trial target
PubChem	Potency	uM	56.234	BAZ2B	-	GI(Protien) :
PubChem	IC50	uM		CBFB	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	Potency	uM	0.355	EHMT2	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	25.119	MAPT	-	GI(Protien) :
PubChem	IC50	uM	4.148	MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	Potency	uM	19.953	POLB	-	GI(Protien) :
PubChem	Potency	uM	10.000	POLH	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	IC50	uM		RUNX1	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	4.611	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	56234.100	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	354.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	12589.300	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	14125.400	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	25118.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	IC50	nM	4147.650	MCL1	-	Target : CHEMBL4361
ChEMBL	Potency	nM	19952.600	POLB	-	Target : CHEMBL2392

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