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Gene Set: D4 : TTD - Alprostadil

Collection D4 : TTD
Chemical Name Alprostadil ( From PubChem : ALPROSTADIL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
354.481 g/mol 3 5 3.4751 True
Structure
InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
InChIKey GMVPRGQOIOIIMI-DWKJAMRDSA-N
Links

Gene (9 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistPTGER2Successful target
TTDAgonistPTGER2Successful target
TTDDrug(s)PTGER2Successful target
TTDDrug(s)PTGER2Successful target
PubChem AR Potency (uM)uM0.024AR-GI(Protien) :
PubChem NoneuMMRGPRX1-GI(Protien) :
PubChem NoneuMRGS4-GI(Protien) :
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
Download gene sets gmt, text, Detailed text
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