Tan Lab | DSigDB

Gene Set: D4 : TTD - Aldosterone

Collection

D4 : TTD

Chemical Name

Aldosterone ( From PubChem : ALDOSTERONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
360.444 g/mol	2	5	1.8457	True

Structure

InChI

InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

InChIKey

PQSUYGKTWSAVDQ-ZVIOFETBSA-N

Links

Gene (16 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			NR3C2		Successful target
TTD	Drug(s)			SLC12A2		Successful target
TTD	Blocker			SLC12A2		Successful target
PubChem	Potency	uM	15.849	AR	-	GI(Protien) :
PubChem	None	uM		ESRRG	-	GI(Protien) :
PubChem	None	uM		HNF4G	-	GI(Protien) :
PubChem	None	uM		NR1D1	-	GI(Protien) :
PubChem	None	uM		NR2C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C2	-	GI(Protien) :
PubChem	None	uM		NR4A2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PGR	-	GI(Protien) :
PubChem	None	uM		PPARA	-	GI(Protien) :
PubChem	None	uM		RORB	-	GI(Protien) :
PubChem	None	uM		RORC	-	GI(Protien) :
PubChem	None	uM		RXRA	-	GI(Protien) :
PubChem	None	uM		RXRA	-	GI(Protien) :
ChEMBL	Activity	-		NR3C1	-	Target : CHEMBL2034

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