Tan Lab | DSigDB

Gene Set: D4 : TTD - 1,2-NAPHTHOQUINONE

Collection

D4 : TTD

Chemical Name

1,2-NAPHTHOQUINONE ( From PubChem : 1,2-NAPHTHOQUINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
158.153 g/mol	0	2	1.4652	True

Structure

InChI

InChI=1S/C10H6O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6H

InChIKey

KETQAJRQOHHATG-UHFFFAOYSA-N

Links

Gene (24 / 44)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			BCHE		Successful target
TTD	Inhibitor			CES1		Research target
TTD	Inhibitor			IDO1		Successful target
TTD	Inhibitor			PTPN1		Research target
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	Potency	uM	14.125	ALDH1A1	-	GI(Protien) :
PubChem	None	uM		APAF1	-	GI(Protien) :
PubChem	Average IC50	uM	10.610	APOBEC3G	-	GI(Protien) :
PubChem	Potency	uM	39.811	BAZ2B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		DLD	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	Potency	uM	8.912	EHMT2	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	7.943	HPGD	-	GI(Protien) :
PubChem	Potency	uM	28.184	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	2.512	MAPT	-	GI(Protien) :
PubChem	Potency	uM	4.467	MAPT	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		STAT3	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	39810.700	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	8912.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	3981.100	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	28183.800	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	14125.400	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	2511.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	4466.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	RECQL	-	Target : CHEMBL1293236

Download gene sets

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