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Gene Set: D4 : TTD - Afatinib

Collection D4 : TTD
Chemical Name Afatinib ( From PubChem : AFATINIB )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
485.938 g/mol 2 7 4.5359 True
Structure
InChI InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
InChIKey ULXXDDBFHOBEHA-CWDCEQMOSA-N
Links

Gene (2 / 9)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDMultitargetEGFRSuccessful target
TTDInhibitorEGFRSuccessful target
TTDDrug(s)EGFRSuccessful target
TTDMultitargetERBB2Successful target
TTDInhibitorERBB2Successful target
TTDDrug(s)ERBB2Successful target
ChEMBLInhibition-EGFR
-Target : CHEMBL203
ChEMBLInhibition-EGFR
-Target : CHEMBL203
ChEMBLInhibition-EGFR
-Target : CHEMBL203
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