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Gene Set: D4 : TTD - SN-38

Collection D4 : TTD
Chemical Name SN-38 ( From PubChem : 7-ETHYL-10-HYDROXYCAMPTOTHECIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
392.405 g/mol 2 7 2.3476 True
Structure
InChI InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1
InChIKey FJHBVJOVLFPMQE-QFIPXVFZSA-N
Links

Gene (1 / 6)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorTOP1Successful target
ChEMBLActivity-TOP1
-Target : CHEMBL1781
ChEMBLActivity-TOP1
-Target : CHEMBL1781
ChEMBLActivity-TOP1
-Target : CHEMBL1781
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
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