DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - ALPHA-NAPHTHOFLAVONE

Collection D4 : TTD
Chemical Name ALPHA-NAPHTHOFLAVONE ( From PubChem : 7,8-BENZOFLAVONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
272.297 g/mol 0 2 4.6132 True
Structure
InChI InChI=1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
InChIKey VFMMPHCGEFXGIP-UHFFFAOYSA-N
Links

Gene (10 / 15)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCYP19A1Successful target
TTDInhibitorPRKDCResearch target
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM1.995CYP2C19-GI(Protien) :
PubChem PotencyuM12.589CYP3A4-GI(Protien) :
PubChem PotencyuM31.623MAPK1-GI(Protien) :
PubChem PotencyuM31.623TP53-GI(Protien) :
PubChem PotencyuM31.623TSHR-GI(Protien) :
ChEMBLInhibition-CYP1B1
-Target : CHEMBL4878
ChEMBLPotencynM1995.300CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM12589.300CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM31622.800MAPK1
-Target : CHEMBL4040
ChEMBLPotencynM31622.800TP53
-Target : CHEMBL4096
ChEMBLPotencynM31622.800TSHR
-Target : CHEMBL1963
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).