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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol

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Collection	D4 : TTD
Chemical Name	(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol ( From PubChem : YC-1 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 304.343 g/mol 1 4 3.8369 True
Structure
InChI	InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
InChIKey	OQQVFCKUDYMWGV-UHFFFAOYSA-N
Links
Gene (18 / 48) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Inhibitor HIF1A Research target PubChem Potency uM 39.811 BAZ2B - GI(Protien) : PubChem Potency uM 39.811 CBX1 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem Potency uM 31.623 CYP2C9 - GI(Protien) : PubChem None uM CYP2C9 - GI(Protien) : PubChem Potency uM 12.589 CYP3A4 - GI(Protien) : PubChem None uM CYP3A4 - GI(Protien) : PubChem Potency uM 11.220 EHMT2 - GI(Protien) : PubChem Potency uM 12.589 EHMT2 - GI(Protien) : PubChem Potency uM 21.192 EHMT2 - GI(Protien) : PubChem AC50_uM uM 10.012 GFER - GI(Protien) : PubChem None uM GFER - GI(Protien) : PubChem Potency uM 12.589 GMNN - GI(Protien) : PubChem Potency uM 12.589 HIF1A - GI(Protien) : PubChem Potency uM 25.119 MPHOSPH8 - GI(Protien) : PubChem Potency uM 8.912 NFKB1 - GI(Protien) : PubChem Potency uM 23.778 RGS4 - GI(Protien) : PubChem None uM RGS4 - GI(Protien) : PubChem None uM RGS4 - GI(Protien) : PubChem None uM SELE - GI(Protien) : PubChem Potency uM 1.032 SMAD3 - GI(Protien) : PubChem Potency uM 2.818 SMAD3 - GI(Protien) : PubChem Potency uM 11.220 TDP1 - GI(Protien) : PubChem Potency uM 17.783 TDP1 - GI(Protien) : ChEMBL Potency nM 39810.700 BAZ2B - Target : CHEMBL1741220 ChEMBL Potency nM 39810.700 CBX1 - Target : CHEMBL1741193 ChEMBL AC50 nM 1584.890 CYP1A2 - Target : CHEMBL3356 ChEMBL AC50 nM 31622.800 CYP2C9 - Target : CHEMBL3397 ChEMBL Potency nM 31622.800 CYP2C9 - Target : CHEMBL3397 ChEMBL AC50 nM 12589.200 CYP3A4 - Target : CHEMBL340 ChEMBL Potency nM 12589.300 CYP3A4 - Target : CHEMBL340 ChEMBL Potency nM 12589.300 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 11220.200 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 21192.300 EHMT2 - Target : CHEMBL6032 ChEMBL AC50 nM 10012.000 GFER - Target : CHEMBL1741189 ChEMBL Potency nM 12589.300 GMNN - Target : CHEMBL1293278 ChEMBL Activity - GUCY1A3 - Target : CHEMBL3137281 ChEMBL Activity - GUCY1A3 - Target : CHEMBL3137281 ChEMBL Activity - GUCY1B3 - Target : CHEMBL3137281 ChEMBL Activity - GUCY1B3 - Target : CHEMBL3137281 ChEMBL Inhibition - HIF1A - Target : CHEMBL4261 ChEMBL Inhibition - HIF1A - Target : CHEMBL4261 ChEMBL Potency nM 12589.300 HIF1A - Target : CHEMBL4261 ChEMBL Potency nM 25118.900 HSD17B10 - Target : CHEMBL4159 ChEMBL Potency nM 25118.900 MPHOSPH8 - Target : CHEMBL1741210 ChEMBL Potency nM 8912.500 NFKB1 - Target : CHEMBL3251
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