Tan Lab | DSigDB

Gene Set: D4 : TTD - Vinpocetine

Collection

D4 : TTD

Chemical Name

Vinpocetine ( From PubChem : VINPOCETINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
350.454 g/mol	0	4	4.0862	True

Structure

InChI

InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1

InChIKey

DDNCQMVWWZOMLN-IRLDBZIGSA-N

Links

Gene (10 / 17)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			PDE1A		Successful target
TTD	Drug(s)			PDE1A		Successful target
TTD	Inhibitor			PDE1B		Successful target
TTD	Drug(s)			PDE1B		Successful target
TTD	Inhibitor			PDE1C		Successful target
TTD	Drug(s)			PDE1C		Successful target
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.883	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM		AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	25.822	AR	-	GI(Protien) :
PubChem	Potency	uM	3.264	DRD1	-	GI(Protien) :
PubChem	Potency	uM	22.387	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	0.141	KCNH2		GI(Protien) :
PubChem	Potency	uM	0.141	KCNH2		GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
ChEMBL	Potency	nM	3264.100	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	22387.200	EHMT2	-	Target : CHEMBL6032

Download gene sets

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