Tan Lab | DSigDB

Gene Set: D4 : TTD - TTNPB

Collection

D4 : TTD

Chemical Name

TTNPB ( From PubChem : TTNPB )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
348.478 g/mol	1	2	6.2943	False(3/4)

Structure

InChI

InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+

InChIKey

Links

Gene (21 / 33)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			RARB		Research target
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	0.013	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		DNMT1	-	GI(Protien) :
PubChem	Potency	uM	15.849	EHMT2	-	GI(Protien) :
PubChem	None	uM		FASN	-	GI(Protien) :
PubChem	Potency	uM	11.220	GMNN	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	27.306	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	10.000	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	26.680	PLK1	-	GI(Protien) :
PubChem	Potency	uM	31.623	POLI	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	Potency	uM	0.708	RXRA	-	GI(Protien) :
PubChem	Potency	uM	31.623	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	3981.100	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	3981.070	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	12.590	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	12.600	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	15848.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	10000.000	NFKB1	-	Target : CHEMBL3251
ChEMBL	Activity	-		RARA	-	Target : CHEMBL2055
ChEMBL	Activity	-		RARB	-	Target : CHEMBL2008
ChEMBL	Activity	-		RARG	-	Target : CHEMBL2003

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