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Gene Set: D4 : TTD - Trimethoprim

Collection D4 : TTD
Chemical Name Trimethoprim ( From PubChem : TRIMETHOPRIM )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotApprovedApprovedApprovedApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
290.318 g/mol 2 7 2.42 True
Structure
InChI InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
InChIKey IEDVJHCEMCRBQM-UHFFFAOYSA-N
Links

Gene (8 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorDHFRSuccessful target
TTDDrug(s)DHFRSuccessful target
TTDInhibitorPDFSuccessful target
TTDDrug(s)PDFSuccessful target
PubChem PotencyuM0.006CBX1-GI(Protien) :
PubChem PotencyuM12.589CYP3A4-GI(Protien) :
ChEMBLPotencynM6.000CBX1
-Target : CHEMBL1741193
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300CYP3A4
-Target : CHEMBL340
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