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Gene Set: D4 : TTD - Topotecan

Collection D4 : TTD
Chemical Name Topotecan ( From PubChem : TOPOTECAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
421.446 g/mol 2 8 1.8468 True
Structure
InChI InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1
InChIKey UCFGDBYHRUNTLO-QHCPKHFHSA-N
Links

Gene (2 / 7)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorTOP1Successful target
TTDDrug(s)TOP1Successful target
ChEMBLInhibition-AKT1
-Target : CHEMBL4282
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
ChEMBLActivity-TOP1
-Target : CHEMBL1781
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