DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Tolazamide

Collection D4 : TTD
Chemical Name Tolazamide ( From PubChem : TOLAZAMIDE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
311.4 g/mol 2 6 3.5744 True
Structure
InChI InChI=1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
InChIKey OUDSBRTVNLOZBN-UHFFFAOYSA-N
Links

Gene (8 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)KCNJ10Successful target
TTDBlockerKCNJ10Successful target
PubChem NoneuMDRD2-GI(Protien) :
PubChem PotencyuM11.220EHMT2-GI(Protien) :
PubChem PotencyuM39.811EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM30.638ESR1-GI(Protien) :
PubChem PotencyuM10.000GLS-GI(Protien) :
PubChem NoneuMMAP1LC3A-GI(Protien) :
PubChem NoneuMMPI-GI(Protien) :
ChEMBLPotencynM39810.700EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM11220.200EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM56234.100KDM4A
-Target : CHEMBL5896
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).