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Gene Set: D4 : TTD - NSC-1771;Thiram

Collection D4 : TTD
Chemical Name NSC-1771;Thiram ( From PubChem : THIRAM )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
240.433 g/mol 0 6 2.0608 True
Structure
InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
InChIKey KUAZQDVKQLNFPE-UHFFFAOYSA-N
Links

Gene (41 / 89)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorJAK2Clinical trial target
PubChem PotencyuM0.079ALDH1A1-GI(Protien) :
PubChem PotencyuM0.126ALDH1A1-GI(Protien) :
PubChem PotencyuM0.501ALDH1A1-GI(Protien) :
PubChem NoneuMAPP-GI(Protien) :
PubChem Potency-Replicate_1uM0.061AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.170AR-GI(Protien) :
PubChem PotencyuM2.512ATXN2-GI(Protien) :
PubChem IC50uMCACNA1B-GI(Protien) :
PubChem Potency-Replicate_1uM0.015CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM0.048CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM0.188CYP19A1-GI(Protien) :
PubChem PotencyuM15.849CYP3A4-GI(Protien) :
PubChem NoneuMDRD3-GI(Protien) :
PubChem PotencyuM1.122EHMT2-GI(Protien) :
PubChem PotencyuM1.259EHMT2-GI(Protien) :
PubChem PotencyuM39.811GAPDH-GI(Protien) :
PubChem NoneuMGAPDH-GI(Protien) :
PubChem PotencyuM1.334GMNN-GI(Protien) :
PubChem PotencyuM21.136GMNN-GI(Protien) :
PubChem NoneuMGNAI1-GI(Protien) :
PubChem PotencyuM0.708HPGD-GI(Protien) :
PubChem PotencyuM1.000HPGD-GI(Protien) :
PubChem AC50_uMuM7.741HSP90AA1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.138HSPB1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.188HSPB1-GI(Protien) :
PubChem PotencyuM1.000HTT-GI(Protien) :
PubChem NoneuMINS-GI(Protien) :
PubChem IC50uM0.223JAK2-GI(Protien) :
PubChem irf1 Inhibition [Ba/F3 cells] (IC50)uM2.375JAK2-GI(Protien) :
PubChem irf1 Inhibition [HEL cells] (IC50)uM13.470JAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem PotencyuM14.125KAT2A-GI(Protien) :
PubChem PotencyuM31.623KAT2A-GI(Protien) :
PubChem PotencyuM44.668KCNH2GI(Protien) :
PubChem PotencyuM44.668KCNH2GI(Protien) :
PubChem NoneuMKCNQ1-GI(Protien) :
PubChem NoneuMMAP1LC3A-GI(Protien) :
PubChem Mean Mutant EC50uM0.080MDM2-GI(Protien) :
PubChem EC50uM0.180MDM2-GI(Protien) :
PubChem Mean Wild-type EC50uM0.400MDM2-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem Potency-Replicate_1uM42.163NFE2L2-GI(Protien) :
PubChem NoneuMNFKBIA-GI(Protien) :
PubChem NoneuMNLRP1-GI(Protien) :
PubChem NoneuMNR2E3-GI(Protien) :
PubChem Ratio Potency (uM)uM0.061NR3C1-GI(Protien) :
PubChem Ratio Potency (uM)uMNR3C1-GI(Protien) :
PubChem PotencyuM14.125PKM-GI(Protien) :
PubChem PotencyuM0.336PLK1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.206PPARD-GI(Protien) :
PubChem Ratio Potency (uM)uM1.100PPARD-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPTGER2-GI(Protien) :
PubChem NoneuMRGS12-GI(Protien) :
PubChem PotencyuM44.668RXRA-GI(Protien) :
PubChem NoneuMSELE-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem PotencyuM0.009TDP1-GI(Protien) :
PubChem PotencyuM0.130TDP1-GI(Protien) :
PubChem PotencyuM0.133TDP1-GI(Protien) :
PubChem PotencyuM0.133TDP1-GI(Protien) :
PubChem PotencyuM0.146TDP1-GI(Protien) :
PubChem PotencyuM0.146TDP1-GI(Protien) :
PubChem PotencyuM2.512VDR-GI(Protien) :
PubChem PotencyuM11.220VDR-GI(Protien) :
ChEMBLPotencynM79.400ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM125.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM501.200ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM15848.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM1258.900EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1122.000EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM39810.700GAPDH
-Target : CHEMBL2284
ChEMBLPotencynM707.900HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM1000.000HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM12589.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM50.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1000.000HTT
-Target : CHEMBL5514
ChEMBLActivityum2.380JAK2
-Target : CHEMBL2971
ChEMBLActivityum13.470JAK2
-Target : CHEMBL2971
ChEMBLIC50nM223.000JAK2
-Target : CHEMBL2971
ChEMBLPotencynM14125.400KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM31622.800KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM25118.900KDM4E
-Target : CHEMBL1293226
ChEMBLEC50nM180.000MDM2
-Target : CHEMBL5023
ChEMBLPotencynM14125.400PKM
-Target : CHEMBL1075189
Download gene sets gmt, text, Detailed text
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