Tan Lab | DSigDB

Gene Set: D4 : TTD - Sifalimumab

Collection

D4 : TTD

Chemical Name

Sifalimumab ( From PubChem : TEMSIROLIMUS )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
1030.29 g/mol	4	17	5.6603	False(1/4)

Structure

InChI

InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3

InChIKey

CBPNZQVSJQDFBE-UHFFFAOYSA-N

Links

Gene (4 / 5)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Drug(s)			IFNAR1		Successful target
TTD	Drug(s)			IFNAR2		Successful target
TTD	Inhibitor			MTOR		Successful target
TTD	Drug(s)			MTOR		Successful target
PubChem	Potency-Replicate_1	uM	23.710	ESR1	-	GI(Protien) :

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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