Tan Lab | DSigDB

Gene Set: D4 : TTD - Telmisartan

Collection

D4 : TTD

Chemical Name

Telmisartan ( From PubChem : TELMISARTAN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
514.617 g/mol	1	6	7.2644	False(2/4)

Structure

InChI

InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)

InChIKey

RMMXLENWKUUMAY-UHFFFAOYSA-N

Links

Gene (9 / 15)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Antagonist			AGTR1		Successful target
TTD	Drug(s)			AGTR1		Successful target
PubChem	Potency	uM	4.467	EHMT2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.708	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.601	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.259	NPSR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.601	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	None	uM		SLC6A3	-	GI(Protien) :
PubChem	None	uM		SLC6A3	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	4466.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1258.900	NPSR1	-	Target : CHEMBL5162

Download gene sets

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