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Gene Set: D4 : TTD - MLN-518

Collection D4 : TTD
Chemical Name MLN-518 ( From PubChem : TANDUTINIB )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
562.703 g/mol 1 10 5.0483 False(2/4)
Structure
InChI InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
InChIKey UXXQOJXBIDBUAC-UHFFFAOYSA-N
Links

Gene (8 / 15)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCSF1RSuccessful target
TTDInhibitorCSF3RSuccessful target
TTDInhibitorFLT3Successful target
TTDInhibitorFLT3Successful target
TTDDrug(s)FLT3Successful target
PubChem NoneuM4.900CSF1R-GI(Protien) :
PubChem NoneuM3.000FLT3-GI(Protien) :
PubChem NoneuM9.100FLT3-GI(Protien) :
PubChem NoneuM2.700KIT-GI(Protien) :
PubChem NoneuM3.800KIT-GI(Protien) :
PubChem Ratio Potency (uM)uM26.601NFE2L2-GI(Protien) :
PubChem NoneuM2.400PDGFRA-GI(Protien) :
PubChem NoneuM4.500PDGFRB-GI(Protien) :
PubChem PotencyuM21.136TDP1-GI(Protien) :
ChEMBLInhibition-FLT3
-Target : CHEMBL1974
Download gene sets gmt, text, Detailed text
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