| Collection |
D4 : TTD |
| Chemical Name |
Sunitinib malate ( From PubChem : S U N I T I N I B M A L A T E ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Approved | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 532.561 g/mol |
6 |
10 |
2.7704 |
False(2/4) |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 2 H 2 7 F N 4 O 2 . C 4 H 6 O 5 / c 1 - 5 - 2 7 ( 6 - 2 ) 1 0 - 9 - 2 4 - 2 2 ( 2 9 ) 2 0 - 1 3 ( 3 ) 1 9 ( 2 5 - 1 4 ( 2 0 ) 4 ) 1 2 - 1 7 - 1 6 - 1 1 - 1 5 ( 2 3 ) 7 - 8 - 1 8 ( 1 6 ) 2 6 - 2 1 ( 1 7 ) 2 8 ; 5 - 2 ( 4 ( 8 ) 9 ) 1 - 3 ( 6 ) 7 / h 7 - 8 , 1 1 - 1 2 , 2 5 H , 5 - 6 , 9 - 1 0 H 2 , 1 - 4 H 3 , ( H , 2 4 , 2 9 ) ( H , 2 6 , 2 8 ) ; 2 , 5 H , 1 H 2 , ( H , 6 , 7 ) ( H , 8 , 9 ) / b 1 7 - 1 2 - ; / t ; 2 - / m . 0 / s 1 |
| InChIKey |
L B W F X V Z L P Y T W Q I - I P O V E D G C S A - N
|
| Links |
|
Gene
(3 /
9)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Multitarget | FLT3 | | | Successful target | | TTD | Inhibitor | FLT3 | | | Successful target | | TTD | Drug(s) | FLT3 | | | Successful target | | TTD | Multitarget | KDR | | | Successful target | | TTD | Inhibitor | KDR | | | Successful target | | TTD | Drug(s) | KDR | | | Successful target | | TTD | Multitarget | KIT | | | Successful target | | TTD | Inhibitor | KIT | | | Successful target | | TTD | Drug(s) | KIT | | | Successful target |
|
| Download gene sets |
gmt, text, Detailed text
|
