Tan Lab | DSigDB

Gene Set: D4 : TTD - SULFURETIN

Collection

D4 : TTD

Chemical Name

SULFURETIN ( From PubChem : SULFURETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
270.237 g/mol	3	5	2.4196	True

Structure

InChI

InChI=1S/C15H10O5/c16-9-2-3-10-13(7-9)20-14(15(10)19)6-8-1-4-11(17)12(18)5-8/h1-7,16-18H/b14-6-

InChIKey

RGNXWPVNPFAADO-NSIKDUERSA-N

Links

Gene (24 / 42)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			MCL1		Clinical trial target
PubChem	IC50_Mean	uM	66.300	ALPI	-	GI(Protien) :
PubChem	None	uM		ALPI	-	GI(Protien) :
PubChem	IC50_Mean	uM	52.900	ALPL	-	GI(Protien) :
PubChem	IC50_Mean	uM	67.200	ALPPL2	-	GI(Protien) :
PubChem	Potency	uM	14.575	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	56.234	BAZ2B	-	GI(Protien) :
PubChem	IC50	uM		CBFB	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	Potency	uM	22.387	GAA	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	8.912	GLS	-	GI(Protien) :
PubChem	AC50_uM	uM	10.510	GSK3A	-	GI(Protien) :
PubChem	None	uM		IDE	-	GI(Protien) :
PubChem	None	uM		IDE	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	IC50	uM	1.535	MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	Potency	uM	19.953	POLH	-	GI(Protien) :
PubChem	Potency	uM	33.808	POLH	-	GI(Protien) :
PubChem	Potency	uM	23.778	POLI	-	GI(Protien) :
PubChem	Potency	uM	28.184	POLK	-	GI(Protien) :
PubChem	IC50	uM	23.800	PSMD14	-	GI(Protien) :
PubChem	None	uM		PSMD14	-	GI(Protien) :
PubChem	None	uM		PSMD14	-	GI(Protien) :
PubChem	IC50	uM	20.560	RACGAP1	-	GI(Protien) :
PubChem	IC50	uM		RUNX1	-	GI(Protien) :
PubChem	EC50_uM	uM	9.630	STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
ChEMBL	IC50	nM	66300.000	ALPI	-	Target : CHEMBL5573
ChEMBL	IC50	nM	52900.000	ALPL	-	Target : CHEMBL5979
ChEMBL	IC50	nM	67200.000	ALPPL2	-	Target : CHEMBL3402
ChEMBL	Potency	nM	22387.200	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	14575.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	56234.100	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	22387.200	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	15848.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224
ChEMBL	IC50	nM	1534.630	MCL1	-	Target : CHEMBL4361

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