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Gene Set: D4 : TTD - Mesalazine

Collection D4 : TTD
Chemical Name Mesalazine ( From PubChem : 5-AMINOSALICYLIC ACID )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
153.135 g/mol 3 4 1.2538 True
Structure
InChI InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
InChIKey KBOPZPXVLCULAV-UHFFFAOYSA-N
Links

Gene (20 / 36)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorPTGS1Successful target
TTDDrug(s)PTGS1Successful target
PubChem NoneuMBCL2L1-GI(Protien) :
PubChem PotencyuM6.310CASP1-GI(Protien) :
PubChem PotencyuM12.589CASP1-GI(Protien) :
PubChem PotencyuM5.012CYP2C19-GI(Protien) :
PubChem NoneuMCYP2C19-GI(Protien) :
PubChem PotencyuM39.811CYP3A4-GI(Protien) :
PubChem PotencyuM3.162EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM68.590ESR1-GI(Protien) :
PubChem NoneuMGAPDH-GI(Protien) :
PubChem PotencyuM15.849GLS-GI(Protien) :
PubChem NoneuMGSTO1-GI(Protien) :
PubChem PotencyuM11.220HPGD-GI(Protien) :
PubChem NoneuMITGA4-GI(Protien) :
PubChem NoneuMMCL1-GI(Protien) :
PubChem NoneuMPADI4-GI(Protien) :
PubChem NoneuMPLA2G7-GI(Protien) :
PubChem PotencyuM1.062POLK-GI(Protien) :
PubChem PotencyuM5.973POLK-GI(Protien) :
PubChem PotencyuM11.220USP1-GI(Protien) :
PubChem PotencyuM39.811USP1-GI(Protien) :
PubChem PotencyuM44.668VDR-GI(Protien) :
ChEMBLPotencynM6309.600CASP1
-Target : CHEMBL4801
ChEMBLPotencynM12589.300CASP1
-Target : CHEMBL4801
ChEMBLPotencynM5011.900CYP2C19
-Target : CHEMBL3622
ChEMBLAC50nM5011.870CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM39810.700CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM3162.300EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM11220.200HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM15848.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM10000.000HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM10000.000HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM7079.500RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM3981.100RECQL
-Target : CHEMBL1293236
Download gene sets gmt, text, Detailed text
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