Tan Lab | DSigDB

Gene Set: D4 : TTD - Staurosporine, N-Benzoyl

Collection

D4 : TTD

Chemical Name

Staurosporine, N-Benzoyl ( From PubChem : MIDOSTAURIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
570.637 g/mol	1	8	6.2356	False(2/4)

Structure

InChI

InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1

InChIKey

BMGQWWVMWDBQGC-IIFHNQTCSA-N

Links

Gene (7 / 9)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CSF1R		Successful target
TTD	Inhibitor			CSF3R		Successful target
TTD	Inhibitor			FLT3		Successful target
PubChem	Potency	uM	0.109	YES1		GI(Protien) :
PubChem	None	uM	6.000	FLT3	-	GI(Protien) :
PubChem	None	uM	6.800	FLT3	-	GI(Protien) :
PubChem	None	uM	7.700	KIT	-	GI(Protien) :
PubChem	None	uM	9.300	PKN1	-	GI(Protien) :
ChEMBL	Inhibition	-		STK32B	-	Target : CHEMBL5912

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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