Gene Set: D4 : TTD - Sparfloxacin
| Collection |
D4 : TTD |
| Chemical Name |
Sparfloxacin ( From PubChem : S P A R F L O X A C I N ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Approved | Not | Not | Approved | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 392.4 g/mol |
3 |
7 |
3.0566 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 1 9 H 2 2 F 2 N 4 O 3 / c 1 - 8 - 5 - 2 4 ( 6 - 9 ( 2 ) 2 3 - 8 ) 1 7 - 1 3 ( 2 0 ) 1 5 ( 2 2 ) 1 2 - 1 6 ( 1 4 ( 1 7 ) 2 1 ) 2 5 ( 1 0 - 3 - 4 - 1 0 ) 7 - 1 1 ( 1 8 ( 1 2 ) 2 6 ) 1 9 ( 2 7 ) 2 8 / h 7 - 1 0 , 2 3 H , 3 - 6 , 2 2 H 2 , 1 - 2 H 3 , ( H , 2 7 , 2 8 ) / t 8 - , 9 + |
| InChIKey |
D Z Z W H B I B M U V I I W - D T O R H V G O S A - N
|
| Links |
|
Gene
(3 /
7)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Multitarget | TOP2A | | | Successful target | | TTD | Inhibitor | TOP2A | | | Successful target | | TTD | Drug(s) | TOP2A | | | Successful target | | TTD | Multitarget | TOP2B | | | Successful target | | TTD | Inhibitor | TOP2B | | | Successful target | | TTD | Drug(s) | TOP2B | | | Successful target | | PubChem | Potency-Replicate_1 | uM | 21.132 | AR | - | | GI(Protien) : |
|
| Download gene sets |
gmt, text, Detailed text
|
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University of Colorado School of Medicine
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