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Gene Set: D4 : TTD - Sotalol

Collection D4 : TTD
Chemical Name Sotalol ( From PubChem : SOTALOL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotApprovedApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
272.364 g/mol 3 5 2.6342 True
Structure
InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3/t12-/m0/s1
InChIKey ZBMZVLHSJCTVON-LBPRGKRZSA-N
Links

Gene (8 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistADRB1Successful target
TTDDrug(s)ADRB1Successful target
PubChem Potency-Replicate_1uM33.492AR-GI(Protien) :
ChEMBLSelectivity-ADRB1
-Target : CHEMBL213
ChEMBLSelectivity-ADRB2
-Target : CHEMBL210
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
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