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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - Recombinant human C1 inhibitor

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Collection	D4 : TTD
Chemical Name	Recombinant human C1 inhibitor ( From PubChem : SILDENAFIL )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 474.576 g/mol 1 9 2.5675 True
Structure
InChI	InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey	BNRNXUUZRGQAQC-UHFFFAOYSA-N
Links
Gene (3 / 6) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Inhibitor C1S Successful target TTD Drug(s) C1S Successful target TTD Inhibitor PDE5A Successful target TTD Drug(s) PDE5A Successful target PubChem Potency uM 5.012 CYP3A4 - GI(Protien) : ChEMBL Potency nM 5011.900 CYP3A4 - Target : CHEMBL340
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