DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - Pazopanib + Tyverb/Tykerb

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Collection	D4 : TTD
Chemical Name	Pazopanib + Tyverb/Tykerb ( From PubChem : SB 243213 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 428.407 g/mol 1 6 5.6371 False(3/4)
Structure
InChI	InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
InChIKey	ZETBBVYSBABLHL-UHFFFAOYSA-N
Links
Gene (6 / 13) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Multitarget EGFR Successful target TTD Inhibitor EGFR Successful target TTD Drug(s) EGFR Successful target TTD Multitarget ERBB2 Successful target TTD Inhibitor ERBB2 Successful target TTD Drug(s) ERBB2 Successful target TTD Inhibitor HTR2A Successful target TTD Agonist HTR2C Successful target TTD Inhibitor HTR2C Successful target TTD Inhibitor HTR6 Clinical trial target PubChem None uM HTR2A GI(Protien) : PubChem None uM HTR2B GI(Protien) : PubChem None uM HTR2C GI(Protien) :
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