Tan Lab | DSigDB

Gene Set: D4 : TTD - Saracatinib

Collection

D4 : TTD

Chemical Name

Saracatinib ( From PubChem : SARACATINIB )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
542.026 g/mol	1	9	3.8883	False(3/4)

Structure

InChI

InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)

InChIKey

OUKYUETWWIPKQR-UHFFFAOYSA-N

Links

Gene (11 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Multitarget			ABL1		Successful target
TTD	Inhibitor			ABL1		Successful target
TTD	Drug(s)			ABL1		Successful target
TTD	Multitarget			ABL2		Successful target
TTD	Inhibitor			ABL2		Successful target
TTD	Drug(s)			ABL2		Successful target
TTD	Inhibitor			CDK2		Clinical trial target
TTD	Inhibitor			EGFR		Successful target
TTD	Inhibitor			KIT		Successful target
TTD	Inhibitor			LCK		Successful target
TTD	Inhibitor			MAP2K1		Successful target
TTD	Inhibitor			MAP2K2		Research target
TTD	Inhibitor			PDGFRA		Discontinued target
TTD	Multitarget			SRC		Successful target
TTD	Inhibitor			SRC		Successful target
TTD	Inhibitor			SRC		Successful target
TTD	Drug(s)			SRC		Successful target
TTD	Inhibitor			YES1		Successful target
PubChem	Potency	uM	0.000	YES1		GI(Protien) :
PubChem	Potency	uM	0.006	YES1	-	GI(Protien) :

Download gene sets

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