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Gene Set: D4 : TTD - 9-Nitrocamptothecin (9-NC)

Collection D4 : TTD
Chemical Name 9-Nitrocamptothecin (9-NC) ( From PubChem : RUBITECAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
393.35 g/mol 1 6 2.511 True
Structure
InChI InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1
InChIKey VHXNKPBCCMUMSW-FQEVSTJZSA-N
Links

Gene (6 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInducerTOP1Successful target
PubChem Potency-Replicate_1uM0.190AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.422AR-GI(Protien) :
PubChem AR Potency (uM)uM0.438AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.596CYP19A1-GI(Protien) :
PubChem ER Potency (uM)uM0.246ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM0.266ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM1.294ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM4.772ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.739NR3C1-GI(Protien) :
PubChem PotencyuM0.034TDP1-GI(Protien) :
PubChem PotencyuM0.211TDP1-GI(Protien) :
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