Tan Lab | DSigDB

Gene Set: D4 : TTD - RU-24969

Collection

D4 : TTD

Chemical Name

RU-24969 ( From PubChem : RU-24969 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
228.29 g/mol	2	2	2.882	True

Structure

InChI

InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3

InChIKey

Links

Gene (12 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			HTR1A		Successful target
TTD	Inhibitor			HTR6		Clinical trial target
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.259	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	Potency	uM	44.668	USP1	-	GI(Protien) :
PubChem	Potency	uM	52.673	USP1	-	GI(Protien) :
ChEMBL	AC50	nM	251.190	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1258.930	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1258.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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