Tan Lab | DSigDB

Gene Set: D4 : TTD - Vitamin A

Collection

D4 : TTD

Chemical Name

Vitamin A ( From PubChem : RETINOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
286.452 g/mol	1	1	5.5103	False(3/4)

Structure

InChI

InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChIKey

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Links

Gene (18 / 39)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Activator			RHO		Research target
PubChem	None	uM		ADRBK1	-	GI(Protien) :
PubChem	Potency	uM	5.967	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	25.119	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.877	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	72.303	AR	-	GI(Protien) :
PubChem	Potency	uM	37.578	CXCL8	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	28.784	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.944	ESR1	-	GI(Protien) :
PubChem	Potency	uM	3.162	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.790	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.485	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	14.960	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	18.122	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.491	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	23.710	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	49.584	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	60.191	HSPB1	-	GI(Protien) :
PubChem	None	uM		HTT	-	GI(Protien) :
PubChem	Potency	uM	14.125	KCNH2		GI(Protien) :
PubChem	Potency	uM	14.125	KCNH2		GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	57.432	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	59.679	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	61.877	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.877	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	68.590	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.818	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.080	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	55.634	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
PubChem	None	uM		UCHL5	-	GI(Protien) :
ChEMBL	Potency	nM	5967.200	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	25118.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Activity	-		RARA	-	Target : CHEMBL2055

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