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Gene Set: D4 : TTD - resveratrol

Collection D4 : TTD
Chemical Name resveratrol ( From PubChem : RESVERATROL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
228.243 g/mol 3 3 2.9738 True
Structure
InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChIKey LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Links

Gene (44 / 122)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)SIRT1Clinical trial target
PubChem Potency-Replicate_1uM5.074AHR-GI(Protien) :
PubChem PotencyuM17.783AHR-GI(Protien) :
PubChem PotencyuM25.119AHR-GI(Protien) :
PubChem Average IC50uM25.310APOBEC3G-GI(Protien) :
PubChem NoneuMAPP-GI(Protien) :
PubChem Potency-Replicate_1uM2.731AR-GI(Protien) :
PubChem Potency-Replicate_1uM6.922AR-GI(Protien) :
PubChem Ratio Potency (uM)uM21.240AR-GI(Protien) :
PubChem Ratio Potency (uM)uM27.539AR-GI(Protien) :
PubChem PotencyuM2.908ATAD5-GI(Protien) :
PubChem PotencyuM14.581ATAD5-GI(Protien) :
PubChem PotencyuM12.589BRCA1-GI(Protien) :
PubChem NoneuMCASP3-GI(Protien) :
PubChem PotencyuM3.981CYP3A4-GI(Protien) :
PubChem PotencyuM7.943EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM0.009ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM1.392ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.442ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM7.167ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM8.747ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM9.688ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM12.303ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM15.496ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM19.496ESR1-GI(Protien) :
PubChem PotencyuM31.623ESR1-GI(Protien) :
PubChem NoneuMESR1-GI(Protien) :
PubChem NoneuMESR2-GI(Protien) :
PubChem AC50_uMuM4.021GFER-GI(Protien) :
PubChem NoneuMGFER-GI(Protien) :
PubChem PotencyuM5.012GLS-GI(Protien) :
PubChem PotencyuM10.000HIF1A-GI(Protien) :
PubChem PotencyuM2.239HTT-GI(Protien) :
PubChem PotencyuM8.912MAPT-GI(Protien) :
PubChem PotencyuM10.000MAPT-GI(Protien) :
PubChem PotencyuM17.783MAPT-GI(Protien) :
PubChem NoneuMMITF-GI(Protien) :
PubChem EC50uMMMP14-GI(Protien) :
PubChem Ratio Potency (uM)uM15.355NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM16.102NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM18.832NFE2L2-GI(Protien) :
PubChem PotencyuM19.331NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM19.331NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM20.334NFE2L2-GI(Protien) :
PubChem PotencyuM37.578NFE2L2-GI(Protien) :
PubChem EC50uM5.203NFKB1-GI(Protien) :
PubChem NoneuMNFKB1-GI(Protien) :
PubChem PotencyuM18.356NPC1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem Potency-Replicate_1uM24.544NR1H4-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem Potency-Replicate_1uM25.119NR1I2-GI(Protien) :
PubChem NoneuMNR5A1-GI(Protien) :
PubChem PotencyuM14.125POLK-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem EC50uM5.203RELA-GI(Protien) :
PubChem NoneuMRELA-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem PotencyuM8.912SMN2-GI(Protien) :
PubChem PotencyuM12.589SMN2-GI(Protien) :
PubChem PotencyuM14.125SMN2-GI(Protien) :
PubChem EC50_uMuM12.330STK33-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem PotencyuM8.052TDP1-GI(Protien) :
PubChem PotencyuM8.200TDP1-GI(Protien) :
PubChem PotencyuM9.200TDP1-GI(Protien) :
PubChem PotencyuM10.000TDP1-GI(Protien) :
PubChem PotencyuM16.360TDP1-GI(Protien) :
PubChem PotencyuM18.837TDP1-GI(Protien) :
PubChem PotencyuM21.136TDP1-GI(Protien) :
PubChem PotencyuM6.310TP53-GI(Protien) :
PubChem PotencyuM10.000TP53-GI(Protien) :
PubChem PotencyuM10.000TP53-GI(Protien) :
PubChem NoneuMUBE2N-GI(Protien) :
ChEMBLActivity-AKT1
-Target : CHEMBL4282
ChEMBLActivity-AKT1
-Target : CHEMBL4282
ChEMBLActivity-AKT1
-Target : CHEMBL4282
ChEMBLPotencynM14581.000ATAD5
-Target : CHEMBL1741209
ChEMBLPotencynM2908.100ATAD5
-Target : CHEMBL1741209
ChEMBLPotencynM3981.100CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM7943.300EHMT2
-Target : CHEMBL6032
ChEMBLActivity-FOXO3
-Target : CHEMBL5778
ChEMBLActivity-FOXO3
-Target : CHEMBL5778
ChEMBLActivity-FOXO3
-Target : CHEMBL5778
ChEMBLActivity-FOXO3
-Target : CHEMBL5778
ChEMBLActivity-FOXO3
-Target : CHEMBL5778
ChEMBLAC50nM4021.000GFER
-Target : CHEMBL1741189
ChEMBLPotencynM10000.000HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2238.700HTT
-Target : CHEMBL5514
ChEMBLPotencynM8912.500MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM10000.000MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM17782.800MAPT
-Target : CHEMBL1293224
ChEMBLEC50nM5203.000NFKB1
-Target : CHEMBL2094258
ChEMBLEC50nM5203.000NFKB2
-Target : CHEMBL2094258
ChEMBLPotencynM18356.400NPC1
-Target : CHEMBL1293277
ChEMBLActivity-PRKCA
-Target : CHEMBL299
ChEMBLEC50nM5203.000RELA
-Target : CHEMBL2094258
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SIRT1
-Target : CHEMBL4506
ChEMBLActivity-SLC2A3
-Target : CHEMBL5215
ChEMBLActivity-SLC2A3
-Target : CHEMBL5215
ChEMBLPotencynM8912.500SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM12589.300SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM14125.400SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM10000.000TP53
-Target : CHEMBL4096
ChEMBLPotencynM10000.000TP53
-Target : CHEMBL4096
ChEMBLPotencynM6309.600TP53
-Target : CHEMBL4096
Download gene sets gmt, text, Detailed text
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Aurora, CO 80045, USA

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