Tan Lab | DSigDB

Gene Set: D4 : TTD - Meglitinides

Collection

D4 : TTD

Chemical Name

Meglitinides ( From PubChem : RACLOPRIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
347.237 g/mol	2	5	3.2505	True

Structure

InChI

InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1

InChIKey

WAOQONBSWFLFPE-VIFPVBQESA-N

Links

Gene (6 / 13)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Drug(s)			INSR		Successful target
TTD	Stimulator			INSR		Successful target
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.259	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
ChEMBL	AC50	nM	1258.930	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1258.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	12589.200	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	12589.300	CYP2D6	-	Target : CHEMBL289

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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