DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Quercetin

Collection D4 : TTD
Chemical Name Quercetin ( From PubChem : QUERCETIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
302.236 g/mol 5 7 1.988 True
Structure
InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
InChIKey REFJWTPEDVJJIY-UHFFFAOYSA-N
Links

Gene (57 / 137)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorPIK3CGClinical trial target
PubChem AhR Potency (uM)uM35.721AHR-GI(Protien) :
PubChem AhR Potency (uM)uM41.987AHR-GI(Protien) :
PubChem Potency-Replicate_1uM54.926AHR-GI(Protien) :
PubChem Potency-Replicate_1uM61.131AHR-GI(Protien) :
PubChem PotencyuM12.589ALDH1A1-GI(Protien) :
PubChem PotencyuM0.794ALOX15-GI(Protien) :
PubChem AR Potency (uM)uM38.885AR-GI(Protien) :
PubChem PotencyuM20.588ATAD5-GI(Protien) :
PubChem PotencyuM28.184BLM-GI(Protien) :
PubChem PotencyuM28.184BLM-GI(Protien) :
PubChem NoneuMCLK3-GI(Protien) :
PubChem NoneuMCSNK1G1-GI(Protien) :
PubChem NoneuMCSNK1G2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM15.849CYP2C19-GI(Protien) :
PubChem PotencyuM7.943CYP2C9-GI(Protien) :
PubChem PotencyuM6.310CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem NoneuMDIRAS1-GI(Protien) :
PubChem PotencyuM4.109DRD1-GI(Protien) :
PubChem PotencyuM12.589EHMT2-GI(Protien) :
PubChem PotencyuM28.184EHMT2-GI(Protien) :
PubChem Ratio Potency (uM)uM10.965ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM11.057ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM13.398ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM17.374ESR1-GI(Protien) :
PubChem Potency-Replicate_1uMESR1-GI(Protien) :
PubChem NoneuMEZH2-GI(Protien) :
PubChem PotencyuM2.378FEN1-GI(Protien) :
PubChem PotencyuM2.378FEN1-GI(Protien) :
PubChem PotencyuM39.811FEN1-GI(Protien) :
PubChem PotencyuM42.129GALK1-GI(Protien) :
PubChem NoneuMGCK-GI(Protien) :
PubChem PotencyuM10.000HIF1A-GI(Protien) :
PubChem PotencyuM8.912HPGD-GI(Protien) :
PubChem PotencyuM19.953HPGD-GI(Protien) :
PubChem NoneuMHSP90AA1-GI(Protien) :
PubChem NoneuMMAP3K5-GI(Protien) :
PubChem PotencyuM2.512MAPT-GI(Protien) :
PubChem PotencyuM3.162MAPT-GI(Protien) :
PubChem PotencyuM7.080MAPT-GI(Protien) :
PubChem PotencyuM8.912MAPT-GI(Protien) :
PubChem PotencyuM11.220MAPT-GI(Protien) :
PubChem PotencyuM12.589MAPT-GI(Protien) :
PubChem NoneuMMAPT-GI(Protien) :
PubChem PotencyuM39.811MPHOSPH8-GI(Protien) :
PubChem NoneuMNEK2-GI(Protien) :
PubChem PotencyuM5.623NFKB1-GI(Protien) :
PubChem Potency-Replicate_1uM49.392NR3C1-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem NoneuMPIM1-GI(Protien) :
PubChem NoneuMPIM2-GI(Protien) :
PubChem PotencyuM0.200POLB-GI(Protien) :
PubChem PotencyuM0.794POLH-GI(Protien) :
PubChem PotencyuM0.562POLI-GI(Protien) :
PubChem PotencyuM79.433POLI-GI(Protien) :
PubChem PotencyuM0.200POLK-GI(Protien) :
PubChem PotencyuM0.282POLK-GI(Protien) :
PubChem PotencyuM0.447POLK-GI(Protien) :
PubChem PotencyuM0.947POLK-GI(Protien) :
PubChem PotencyuM1.122POLK-GI(Protien) :
PubChem PotencyuM2.818POLK-GI(Protien) :
PubChem NoneuMRNASEH1-GI(Protien) :
PubChem NoneuMSLK-GI(Protien) :
PubChem NoneuMSTK16-GI(Protien) :
PubChem PotencyuM1.836TDP1-GI(Protien) :
PubChem PotencyuM12.589TDP1-GI(Protien) :
PubChem PotencyuM12.589TDP1-GI(Protien) :
PubChem PotencyuM14.581TDP1-GI(Protien) :
PubChem PotencyuM26.609TDP1-GI(Protien) :
PubChem PotencyuM15.410YES1GI(Protien) :
PubChem NoneuMYWHAB-GI(Protien) :
ChEMBLPotencynM12589.300ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM794.300ALOX15
-Target : CHEMBL2903
ChEMBLActivity-ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM15848.900ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM12589.300ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM20587.800ATAD5
-Target : CHEMBL1741209
ChEMBLInhibition-AVPR2
-Target : CHEMBL1790
ChEMBLInhibition-AVPR2
-Target : CHEMBL1790
ChEMBLPotencynM28183.800BLM
-Target : CHEMBL1293237
ChEMBLPotencynM28183.800BLM
-Target : CHEMBL1293237
ChEMBLAC50nM316.230CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM15848.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM7943.300CYP2C9
-Target : CHEMBL3397
ChEMBLAC50nM15848.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM6309.600CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM4109.200DRD1
-Target : CHEMBL2056
ChEMBLPotencynM28183.800EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM12589.300EHMT2
-Target : CHEMBL6032
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLInhibition-F2
-Target : CHEMBL204
ChEMBLPotencynM2377.800FEN1
-Target : CHEMBL5027
ChEMBLPotencynM42128.500GALK1
-Target : CHEMBL1293257
ChEMBLActivity-GPR35
-Target : CHEMBL1293267
ChEMBLPotencynM10000.000HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM8912.500HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM19952.600HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM158.500HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1000.000HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM125.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM251.200HSD17B10
-Target : CHEMBL4159
ChEMBLActivity-HSF1
-Target : CHEMBL5869
ChEMBLActivity-HSPB1
-Target : CHEMBL5976
ChEMBLPotencynM8912.500KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM14125.400KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM10000.000KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM17782.800MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM11220.200MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM10000.000MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM2511.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM5011.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM3162.300MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM11220.200MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM7079.500MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM12589.300MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM8912.500MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM39810.700MPHOSPH8
-Target : CHEMBL1741210
ChEMBLPotencynM5623.400NFKB1
-Target : CHEMBL3251
ChEMBLInhibition-PIK3CA
-Target : CHEMBL4005
ChEMBLInhibition-PIK3CA
-Target : CHEMBL4005
ChEMBLPotencynM199.500POLB
-Target : CHEMBL2392
ChEMBLActivity-PON1
-Target : CHEMBL3167
ChEMBLPotencynM2511.900RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM1778.300RECQL
-Target : CHEMBL1293236
ChEMBLActivity-TOP1
-Target : CHEMBL1781
ChEMBLActivity-TOP2A
-Target : CHEMBL1806
ChEMBLActivity-TOP2A
-Target : CHEMBL1806
ChEMBLInhibition-XDH
-Target : CHEMBL1929
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).