Tan Lab | DSigDB

Gene Set: D4 : TTD - Budesonide

Collection

D4 : TTD

Chemical Name

Budesonide ( From PubChem : PULMICORT NEBUAMP )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
430.534 g/mol	2	6	2.7168	True

Structure

InChI

InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21-,22+,23-,24-,25+/m0/s1

InChIKey

VOVIALXJUBGFJZ-AMTWPJRWSA-N

Links

Gene (13 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Antagonist			NR3C1		Successful target
TTD	Drug(s)			NR3C1		Successful target
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP3A4	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MAP3K3	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	None	uM		STAT3	-	GI(Protien) :
PubChem	None	uM		TRHR	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340

Download gene sets

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