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Gene Set: D4 : TTD - Propylthiouracil

Collection D4 : TTD
Chemical Name Propylthiouracil ( From PubChem : PROPYLTHIOURACIL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotApprovedNotApprovedApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
170.232 g/mol 2 2 1.385 True
Structure
InChI InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChIKey KNAHARQHSZJURB-UHFFFAOYSA-N
Links

Gene (7 / 10)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorDIO1Successful target
TTDDrug(s)DIO1Successful target
TTDInhibitorTPOSuccessful target
TTDInhibitorTPOSuccessful target
TTDDrug(s)TPOSuccessful target
PubChem Potency-Replicate_1uM26.603ESR1-GI(Protien) :
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
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