Tan Lab | DSigDB

Gene Set: D4 : TTD - Propidium

Collection

D4 : TTD

Chemical Name

Propidium ( From PubChem : PROPIDIUM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
414.586 g/mol	2	2	6.1508	False(3/4)

Structure

InChI

InChI=1S/C27H33N4/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3/q+1/p+1

InChIKey

ZDWVWKDAWBGPDN-UHFFFAOYSA-O

Links

Gene (22 / 46)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ACHE		Successful target
PubChem	Potency	uM	11.220	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	5.012	BLM	-	GI(Protien) :
PubChem	Potency	uM	1.117	CBFB	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.585	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	6.310	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	5.012	EHMT2	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	Potency	uM	12.589	KMT2A	-	GI(Protien) :
PubChem	Potency	uM	1.259	MAPT	-	GI(Protien) :
PubChem	Potency	uM	6.310	MAPT	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Potency	uM	12.589	MEN1	-	GI(Protien) :
PubChem	Potency	uM	6.310	POLK	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	Potency	uM	1.117	RUNX1	-	GI(Protien) :
PubChem	Potency	uM	2.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	2.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	44.668	THRB	-	GI(Protien) :
PubChem	Potency	uM	7.943	USP1	-	GI(Protien) :
PubChem	Potency	uM	8.912	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	5011.900	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	1117.500	CBFB	-	Target : CHEMBL2093862
ChEMBL	AC50	nM	12589.200	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1584.890	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1584.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	6309.570	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	6309.600	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5011.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	12589.300	KMT2A	-	Target : CHEMBL2093861
ChEMBL	Potency	nM	6309.600	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	1258.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	MEN1	-	Target : CHEMBL2093861
ChEMBL	Potency	nM	35481.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	11220.200	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	1117.500	RUNX1	-	Target : CHEMBL2093862
ChEMBL	Potency	nM	44668.400	THRB	-	Target : CHEMBL1947

Download gene sets

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