Tan Lab | DSigDB

Gene Set: D4 : TTD - Prednisolone

Collection

D4 : TTD

Chemical Name

Prednisolone ( From PubChem : PREDNISOLONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
360.444 g/mol	3	5	1.5576	True

Structure

InChI

InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChIKey

OIGNJSKKLXVSLS-VWUMJDOOSA-N

Links

Gene (7 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Drug(s)			SERPINA6		Successful target
PubChem	Ratio Potency (uM)	uM	0.030	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.039	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.039	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.048	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.055	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.068	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.073	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.084	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.085	AR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		ITGA4	-	GI(Protien) :
PubChem	Potency	uM	0.058	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.073	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.022	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.024	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.032	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.056	NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	58.000	NFE2L2	-	Target : CHEMBL1075094

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