Tan Lab | DSigDB

Gene Set: D4 : TTD - Prazepam

Collection

D4 : TTD

Chemical Name

Prazepam ( From PubChem : PRAZEPAM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	4

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
324.804 g/mol	0	3	3.4346	True

Structure

InChI

InChI=1S/C19H17ClN2O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)21-11-18(23)22(17)12-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2

InChIKey

Links

Gene (8 / 16)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Antagonist			GABRA1		Successful target
TTD	Drug(s)			GABRA1		Successful target
PubChem	Potency-Replicate_1	uM	21.314	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	22.148	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	40.827	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	42.424	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	64.150	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	45.808	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	51.398	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	32.151	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	42.874	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	45.808	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :

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