DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - PF-05212384

Collection D4 : TTD
Chemical Name PF-05212384 ( From PubChem : PKI-587 )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
615.726 g/mol 2 13 3.2359 False(2/4)
Structure
InChI InChI=1S/C32H41N9O4/c1-38(2)27-11-13-39(14-12-27)29(42)24-5-9-26(10-6-24)34-32(43)33-25-7-3-23(4-8-25)28-35-30(40-15-19-44-20-16-40)37-31(36-28)41-17-21-45-22-18-41/h3-10,27H,11-22H2,1-2H3,(H2,33,34,43)
InChIKey DWZAEMINVBZMHQ-UHFFFAOYSA-N
Links

Gene (5 / 8)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)MTORSuccessful target
TTDDrug(s)PIK3CGClinical trial target
ChEMBLActivity-AKT1
-Target : CHEMBL4282
ChEMBLActivity-AKT1
-Target : CHEMBL4282
ChEMBLActivity-AKT1S1
-Target : CHEMBL1255161
ChEMBLActivity-MTOR
-Target : CHEMBL2842
ChEMBLActivity-MTOR
-Target : CHEMBL2842
ChEMBLActivity-NOS3
-Target : CHEMBL4803
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).