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Gene Set: D4 : TTD - Piretanide

Collection D4 : TTD
Chemical Name Piretanide ( From PubChem : PIRETANIDE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
362.4 g/mol 2 7 4.2708 True
Structure
InChI InChI=1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)
InChIKey UJEWTUDSLQGTOA-UHFFFAOYSA-N
Links

Gene (10 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDBlockerSLC12A1Successful target
PubChem Potency-Replicate_1uM11.359AR-GI(Protien) :
PubChem PotencyuM17.783EHMT2-GI(Protien) :
PubChem PotencyuM1.000HIF1A-GI(Protien) :
PubChem Ratio Potency (uM)uM8.757NR3C1-GI(Protien) :
PubChem Potency-Replicate_1uM9.099NR3C1-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem NoneuMPAFAH1B2-GI(Protien) :
PubChem NoneuMTNNC1-GI(Protien) :
PubChem NoneuMTNNI3-GI(Protien) :
PubChem NoneuMTNNT2-GI(Protien) :
ChEMBLPotencynM17782.800EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1000.000HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM12589.300HSD17B10
-Target : CHEMBL4159
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