Gene Set: D4 : TTD - PD-0166326;PD-166326
| Collection |
D4 : TTD |
| Chemical Name |
PD-0166326;PD-166326 ( From PubChem : U N I I - 0 H 7 7 F 2 T 4 U 3 ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 427.283 g/mol |
2 |
5 |
4.6112 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 1 H 1 6 C l 2 N 4 O 2 / c 1 - 2 7 - 1 9 - 1 3 ( 9 - 1 5 ( 2 0 ( 2 7 ) 2 9 ) 1 8 - 1 6 ( 2 2 ) 6 - 3 - 7 - 1 7 ( 1 8 ) 2 3 ) 1 0 - 2 4 - 2 1 ( 2 6 - 1 9 ) 2 5 - 1 4 - 5 - 2 - 4 - 1 2 ( 8 - 1 4 ) 1 1 - 2 8 / h 2 - 1 0 , 2 8 H , 1 1 H 2 , 1 H 3 , ( H , 2 4 , 2 5 , 2 6 ) |
| InChIKey |
Z I Q F Y V P V J Z E O F S - U H F F F A O Y S A - N
|
| Links |
|
Gene
(10 /
10)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | ABL1 | | | Successful target | | TTD | Inhibitor | ABL2 | | | Successful target | | TTD | Inhibitor | EGFR | | | Successful target | | TTD | Inhibitor | FGFR1 | | | Clinical trial target | | TTD | Inhibitor | KIT | | | Successful target | | TTD | Inhibitor | LCK | | | Successful target | | TTD | Inhibitor | MAPK14 | | | Clinical trial target | | TTD | Inhibitor | PDGFRA | | | Discontinued target | | TTD | Inhibitor | PDGFRB | | | Research target | | TTD | Inhibitor | SRC | | | Successful target |
|
| Download gene sets |
gmt, text, Detailed text
|
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA
* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).
