Tan Lab | DSigDB

Gene Set: D4 : TTD - PD-173074

Collection

D4 : TTD

Chemical Name

PD-173074 ( From PubChem : PD 173074 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
523.67 g/mol	3	10	5.6998	False(2/4)

Structure

InChI

InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)

InChIKey

DXCUKNQANPLTEJ-UHFFFAOYSA-N

Links

Gene (17 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			FGFR1		Clinical trial target
TTD	Inhibitor			FGFR2		Successful target
TTD	Inhibitor			FGFR3		Clinical trial target
TTD	Inhibitor			FGFR4		Research target
TTD	Inhibitor			FLT1		Clinical trial target
TTD	Inhibitor			FLT4		Successful target
TTD	Inhibitor			KDR		Successful target
TTD	Inhibitor			PDGFRA		Discontinued target
TTD	Inhibitor			PDGFRB		Research target
TTD	Inhibitor			SRC		Successful target
PubChem	Potency	uM	8.912	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	16.360	IDH1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	9.723	YES1		GI(Protien) :

Download gene sets

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