Tan Lab | DSigDB

Gene Set: D4 : CTD - mitonafide

Collection

D4 : CTD

Chemical Name

mitonafide ( From PubChem : MITONAFIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
313.308 g/mol	0	4	1.9457	True

Structure

InChI

InChI=1S/C16H15N3O4/c1-17(2)6-7-18-15(20)12-5-3-4-10-8-11(19(22)23)9-13(14(10)12)16(18)21/h3-5,8-9H,6-7H2,1-2H3

InChIKey

Links

Gene (24 / 31)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(cleavage)			CASP3		C019215
CTD	decreases(expression)			MAPK1		C019215
CTD	increases(phosphorylation)			MAPK1		C019215
CTD	decreases(expression)			MAPK3		C019215
CTD	increases(phosphorylation)			MAPK3		C019215
CTD	increases(expression)			TP53		C019215
PubChem	None	uM		DNMT1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	Potency	uM	7.943	ERG	-	GI(Protien) :
PubChem	Potency	uM	19.953	FEN1	-	GI(Protien) :
PubChem	Potency	uM	1.778	GLP1R	-	GI(Protien) :
PubChem	Potency	uM	1.458	GMNN	-	GI(Protien) :
PubChem	Potency	uM	10.322	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	Potency	uM	1.636	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	2.593	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PABPC1	-	GI(Protien) :
PubChem	Potency	uM	79.433	POLI	-	GI(Protien) :
PubChem	None	uM		SENP1	-	GI(Protien) :
PubChem	Potency	uM	6.310	SMAD3	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	Potency	uM	0.206	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.259	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	1636.000	NFE2L2	-	Target : CHEMBL1075094

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