Tan Lab | DSigDB

Gene Set: D4 : CTD - 4-phenylphenol

Collection

D4 : CTD

Chemical Name

4-phenylphenol ( From PubChem : 4-PHENYLPHENOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
170.207 g/mol	1	1	3.0592	True

Structure

InChI

InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H

InChIKey

Links

Gene (9 / 25)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			AR		C019046
CTD	decreases(reaction)			AR		C019046
CTD	affects(binding)			ESR1		C019046
CTD	increases(activity)			ESR1		C019046
CTD	increases(expression)			ESR1		C019046
CTD	increases(expression)			ESR2		C019046
CTD	increases(expression)			PGR		C019046
CTD	increases(expression)			TFF1		C019046
CTD	increases(glucuronidation)			UGT2B11		C019046
CTD	increases(glucuronidation)			UGT2B15		C019046
CTD	increases(metabolic processing)			UGT2B15		C019046
PubChem	AR Potency (uM)	uM	40.856	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.320	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.436	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.521	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.229	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.584	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	28.235	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	47.134	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.690	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	22.975	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	53.763	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	53.763	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.488	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

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