Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-tert-butylhydroquinone

Collection

D4 : CTD

Chemical Name

2-tert-butylhydroquinone ( From PubChem : TERT-BUTYLHYDROQUINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
166.217 g/mol	2	2	2.3953	True

Structure

InChI

InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3

InChIKey

BGNXCDMCOKJUMV-UHFFFAOYSA-N

Links

Gene (42 / 137)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCC1		C018855
CTD	increases(expression)			ABCC2		C018855
CTD	increases(expression)			ABCG2		C018855
CTD	increases(reaction)			ABCG2		C018855
CTD	increases(expression)			AHR		C018855
CTD	increases(reaction)			AHR		C018855
CTD	increases(expression)			AHR		C018855
CTD	increases(reaction)			AHR		C018855
CTD	increases(expression)			AKR1C1		C018855
CTD	decreases(reaction)			AR		C018855
CTD	increases(activity)			AR		C018855
CTD	increases(expression)			BCL2		C018855
CTD	increases(expression)			CD86		C018855
CTD	increases(activity)			CES1		C018855
CTD	increases(expression)			CES1		C018855
CTD	affects(reaction)			CES1		C018855
CTD	affects(binding)			CREBBP		C018855
CTD	decreases(reaction)			CREBBP		C018855
CTD	increases(reaction)			CREBBP		C018855
CTD	affects(binding)			CUL3		C018855
CTD	decreases(reaction)			CUL3		C018855
CTD	decreases(reaction)			CYP1A1		C018855
CTD	increases(activity)			CYP1A1		C018855
CTD	increases(expression)			CYP1A1		C018855
CTD	increases(reaction)			CYP1A1		C018855
CTD	increases(activity)			CYP1A1		C018855
CTD	increases(expression)			CYP1A1		C018855
CTD	affects(localization)			GABPA		C018855
CTD	affects(expression)			GCLC		C018855
CTD	increases(expression)			GCLM		C018855
CTD	increases(activity)			GSR		C018855
CTD	increases(expression)			GSTM1		C018855
CTD	increases(expression)			GSTP1		C018855
CTD	increases(expression)			HBG1		C018855
CTD	affects(binding)			HMOX1		C018855
CTD	decreases(reaction)			HMOX1		C018855
CTD	increases(reaction)			HMOX1		C018855
CTD	increases(expression)			HMOX1		C018855
CTD	affects(cotreatment)			HMOX1		C018855
CTD	increases(expression)			HMOX1		C018855
CTD	increases(expression)			HMOX1		C018855
CTD	increases(expression)			HMOX1		C018855
CTD	affects(reaction)			HMOX1		C018855
CTD	decreases(reaction)			HMOX1		C018855
CTD	increases(expression)			HMOX1		C018855
CTD	decreases(expression)			IL2		C018855
CTD	decreases(secretion)			IL2		C018855
CTD	decreases(expression)			IL2RA		C018855
CTD	affects(binding)			KEAP1		C018855
CTD	decreases(reaction)			KEAP1		C018855
CTD	increases(ubiquitination)			KEAP1		C018855
CTD	increases(reaction)			KEAP1		C018855
CTD	increases(expression)			KEAP1		C018855
CTD	affects(binding)			NFE2L2		C018855
CTD	decreases(reaction)			NFE2L2		C018855
CTD	increases(reaction)			NFE2L2		C018855
CTD	increases(activity)			NFE2L2		C018855
CTD	affects(localization)			NFE2L2		C018855
CTD	increases(activity)			NFE2L2		C018855
CTD	decreases(reaction)			NFE2L2		C018855
CTD	increases(ubiquitination)			NFE2L2		C018855
CTD	affects(binding)			NFE2L2		C018855
CTD	increases(reaction)			NFE2L2		C018855
CTD	affects(binding)			NFE2L2		C018855
CTD	increases(reaction)			NFE2L2		C018855
CTD	increases(activity)			NFE2L2		C018855
CTD	decreases(response to substance)			NFE2L2		C018855
CTD	increases(activity)			NFE2L2		C018855
CTD	affects(localization)			NFE2L2		C018855
CTD	increases(expression)			NFE2L2		C018855
CTD	increases(expression)			NFE2L2		C018855
CTD	decreases(response to substance)			NFE2L2		C018855
CTD	increases(expression)			NFE2L2		C018855
CTD	affects(localization)			NFE2L2		C018855
CTD	increases(stability)			NFE2L2		C018855
CTD	decreases(reaction)			NFE2L2		C018855
CTD	affects(reaction)			NFE2L2		C018855
CTD	decreases(reaction)			NFE2L2		C018855
CTD	increases(expression)			NFE2L2		C018855
CTD	affects(reaction)			NFE2L2		C018855
CTD	increases(expression)			NFE2L2		C018855
CTD	affects(binding)			NQO1		C018855
CTD	increases(reaction)			NQO1		C018855
CTD	increases(activity)			NQO1		C018855
CTD	increases(expression)			NQO1		C018855
CTD	decreases(reaction)			NQO1		C018855
CTD	increases(expression)			NQO1		C018855
CTD	affects(reaction)			NQO1		C018855
CTD	increases(expression)			NQO1		C018855
CTD	affects(binding)			NR1I3		C018855
CTD	decreases(activity)			NR1I3		C018855
CTD	increases(expression)			TXNRD1		C018855
CTD	increases(activity)			UGT1A6		C018855
CTD	increases(expression)			UGT1A6		C018855
CTD	increases(expression)			UGT1A6		C018855
CTD	increases(reaction)			UGT1A6		C018855
CTD	increases(expression)			UGT1A9		C018855
CTD	increases(expression)			UGT2B7		C018855
PubChem	Potency-Replicate_1	uM	13.333	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	16.785	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	17.780	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	20.087	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.690	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	31.231	AHR	-	GI(Protien) :
PubChem	Potency	uM	0.079	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	1.995	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	3.548	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	19.953	ALOX15	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	18.996	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	AR	-	GI(Protien) :
PubChem	Potency	uM	66.824	CXCL8	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	4.467	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	29.855	GMNN	-	GI(Protien) :
PubChem	None	uM		HTT	-	GI(Protien) :
PubChem	Potency	uM	2.731	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.857	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	5.661	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.324	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	10.591	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	13.333	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	35.481	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.941	PPARD	-	GI(Protien) :
PubChem	Potency	uM	44.668	PPARG	-	GI(Protien) :
PubChem	Potency	uM	1.189	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.679	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	3548.100	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	79.400	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	1995.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	19952.600	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	4466.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	3162.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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