Tan Lab | DSigDB

Gene Set: D4 : CTD - salvin

Collection

D4 : CTD

Chemical Name

salvin ( From PubChem : CARNOSIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
332.434 g/mol	3	4	4.3161	True

Structure

InChI

InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1

InChIKey

Links

Gene (15 / 31)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(phosphorylation)			BAD		C018381
CTD	increases(reaction)			BAD		C018381
CTD	increases(activity)			CASP9		C018381
CTD	increases(reaction)			CASP9		C018381
CTD	affects(cotreatment)			CD14		C018381
CTD	increases(expression)			CD14		C018381
CTD	increases(reaction)			CD14		C018381
CTD	increases(expression)			CDKN1B		C018381
CTD	increases(reaction)			CDKN1B		C018381
CTD	affects(cotreatment)			ITGAM		C018381
CTD	increases(expression)			ITGAM		C018381
CTD	increases(reaction)			ITGAM		C018381
CTD	increases(activity)			PPARG		C018381
CTD	increases(expression)			PTEN		C018381
CTD	increases(reaction)			PTEN		C018381
CTD	affects(cotreatment)			RARA		C018381
CTD	increases(expression)			RARA		C018381
CTD	increases(expression)			RXRA		C018381
CTD	increases(reaction)			RXRA		C018381
CTD	increases(expression)			VDR		C018381
CTD	increases(reaction)			VDR		C018381
PubChem	Potency	uM	14.125	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	3.548	EHMT2	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	15.849	HPGD	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	19.953	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	3548.100	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15848.900	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224

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