Tan Lab | DSigDB

Gene Set: D4 : CTD - HOE 33342

Collection

D4 : CTD

Chemical Name

HOE 33342 ( From PubChem : HOECHST 33342 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
452.551 g/mol	2	5	4.9266	True

Structure

InChI

InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31)

InChIKey

PRDFBSVERLRRMY-UHFFFAOYSA-N

Links

Gene (10 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ABCB11		C017807
CTD	increases(transport)			ABCB11		C017807
CTD	decreases(activity)			ABCB11		C017807
CTD	decreases(abundance)			ABCG2		C017807
CTD	increases(transport)			ABCG2		C017807
CTD	decreases(reaction)			ABCG2		C017807
PubChem	Potency	uM	12.589	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	11.220	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	2.818	MAPT	-	GI(Protien) :
PubChem	Potency	uM	0.299	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.631	POLK	-	GI(Protien) :
PubChem	Potency	uM	3.981	SMN2	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	2818.400	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	28183.800	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	3981.100	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

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