Tan Lab | DSigDB

Gene Set: D4 : CTD - tris(1,3-dichloro-2-propyl)phosphate

Collection

D4 : CTD

Chemical Name

tris(1,3-dichloro-2-propyl)phosphate ( From PubChem : FYROL FR 2 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
430.905 g/mol	0	4	4.6829	True

Structure

InChI

InChI=1S/C9H15Cl6O4P/c10-1-7(2-11)17-20(16,18-8(3-12)4-13)19-9(5-14)6-15/h7-9H,1-6H2

InChIKey

Links

Gene (10 / 27)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			AR		C016805
CTD	decreases(activity)			AR		C016805
CTD	decreases(activity)			AR		C016805
CTD	increases(expression)			CYP11A1		C016805
CTD	increases(expression)			CYP19A1		C016805
CTD	affects(binding)			ESR1		C016805
CTD	increases(activity)			ESR1		C016805
CTD	increases(activity)			ESR1		C016805
CTD	increases(expression)			HSD3B2		C016805
CTD	increases(activity)			NR1I2		C016805
CTD	decreases(activity)			NR3C1		C016805
CTD	affects(binding)			PGR		C016805
CTD	decreases(activity)			PGR		C016805
CTD	decreases(expression)			SULT1E1		C016805
CTD	decreases(expression)			SULT2A1		C016805
PubChem	Potency-Replicate_1	uM	38.691	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	40.204	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.641	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	47.123	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	68.241	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	68.590	AR	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.941	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.757	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.896	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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