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Gene Set: D4 : CTD - lonidamine

Collection D4 : CTD
Chemical Name lonidamine ( From PubChem : LONIDAMINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
321.158 g/mol 1 4 4.0896 True
Structure
InChI InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
InChIKey WDRYRZXSPDWGEB-UHFFFAOYSA-N
Links

Gene (23 / 63)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(reaction)AKT1
C016371
CTDincreases(phosphorylation)AKT1
C016371
CTDdecreases(phosphorylation)AKT1
C016371
CTDincreases(reaction)AKT1
C016371
CTDaffects(localization)BAX
C016371
CTDincreases(reaction)BAX
C016371
CTDaffects(localization)BAX
C016371
CTDaffects(cotreatment)BCL2
C016371
CTDdecreases(reaction)BCL2
C016371
CTDincreases(activity)BCL2
C016371
CTDincreases(cleavage)BCL2
C016371
CTDincreases(reaction)BCL2
C016371
CTDdecreases(expression)BCL2L1
C016371
CTDaffects(cotreatment)BID
C016371
CTDincreases(activity)BID
C016371
CTDincreases(cleavage)BID
C016371
CTDincreases(activity)BID
C016371
CTDaffects(cotreatment)CASP3
C016371
CTDincreases(activity)CASP3
C016371
CTDincreases(cleavage)CASP3
C016371
CTDaffects(cotreatment)CASP3
C016371
CTDincreases(cleavage)CASP3
C016371
CTDaffects(cotreatment)CASP8
C016371
CTDincreases(activity)CASP8
C016371
CTDincreases(cleavage)CASP8
C016371
CTDdecreases(reaction)CASP8
C016371
CTDincreases(activity)CASP9
C016371
CTDincreases(cleavage)CASP9
C016371
CTDincreases(reaction)CASP9
C016371
CTDdecreases(reaction)CASP9
C016371
CTDaffects(cotreatment)CASP9
C016371
CTDincreases(cleavage)CASP9
C016371
CTDdecreases(activity)CFTR
C016371
CTDaffects(cotreatment)HTRA2
C016371
CTDaffects(localization)HTRA2
C016371
CTDdecreases(reaction)MAPK1
C016371
CTDincreases(phosphorylation)MAPK1
C016371
CTDdecreases(reaction)MAPK3
C016371
CTDincreases(phosphorylation)MAPK3
C016371
CTDdecreases(expression)MCL1
C016371
CTDdecreases(reaction)RPS6
C016371
CTDincreases(phosphorylation)RPS6
C016371
CTDdecreases(reaction)RPS6KB1
C016371
CTDincreases(phosphorylation)RPS6KB1
C016371
CTDincreases(phosphorylation)STK11
C016371
CTDdecreases(expression)XIAP
C016371
CTDincreases(reaction)XIAP
C016371
CTDdecreases(expression)XIAP
C016371
CTDincreases(reaction)XIAP
C016371
CTDdecreases(expression)XIAP
C016371
PubChem PotencyuM2.239EHMT2-GI(Protien) :
PubChem PotencyuM31.623EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM0.095ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.682ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM23.891ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM18.832NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM54.095NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM43.353NR3C1-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem PotencyuM39.811TSHR-GI(Protien) :
ChEMBLPotencynM31622.800EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM2238.700EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM39810.700TSHR
-Target : CHEMBL1963
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Aurora, CO 80045, USA

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