Tan Lab | DSigDB

Gene Set: D4 : CTD - o,p'-DDT

Collection

D4 : CTD

Chemical Name

o,p'-DDT ( From PubChem : O,P'-DDT )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
354.486 g/mol	0	0	6.4955	False(3/4)

Structure

InChI

InChI=1S/C14H9Cl5/c15-10-7-5-9(6-8-10)13(14(17,18)19)11-3-1-2-4-12(11)16/h1-8,13H/t13-/m1/s1

InChIKey

CVUGPAFCQJIYDT-CYBMUJFWSA-N

Links

Gene (178 / 273)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ABCB1		C016340
CTD	increases(expression)			ABCB1		C016340
CTD	increases(expression)			ABCC2		C016340
CTD	decreases(activity)			ABCG2		C016340
CTD	increases(expression)			ABCG2		C016340
CTD	increases(expression)			ADAMTS9		C016340
CTD	increases(expression)			AKR1C2		C016340
CTD	decreases(expression)			ALPK2		C016340
CTD	increases(expression)			ANAPC1		C016340
CTD	increases(expression)			ANO1		C016340
CTD	increases(expression)			AP1AR		C016340
CTD	decreases(reaction)			AR		C016340
CTD	increases(activity)			AR		C016340
CTD	affects(binding)			AR		C016340
CTD	decreases(activity)			AR		C016340
CTD	affects(binding)			AR		C016340
CTD	affects(binding)			AR		C016340
CTD	decreases(reaction)			AR		C016340
CTD	increases(activity)			AR		C016340
CTD	affects(binding)			AR		C016340
CTD	decreases(reaction)			AR		C016340
CTD	decreases(reaction)			AR		C016340
CTD	increases(activity)			AR		C016340
CTD	decreases(activity)			AR		C016340
CTD	decreases(expression)			ARNT2		C016340
CTD	decreases(reaction)			ARNT2		C016340
CTD	decreases(expression)			ASPM		C016340
CTD	increases(expression)			ASRGL1		C016340
CTD	decreases(reaction)			BCL2		C016340
CTD	increases(expression)			BCL2		C016340
CTD	increases(expression)			BCL2		C016340
CTD	increases(expression)			BEX2		C016340
CTD	increases(expression)			BNIP1		C016340
CTD	decreases(reaction)			BRCA1		C016340
CTD	increases(expression)			BRCA1		C016340
CTD	increases(expression)			C22ORF29		C016340
CTD	decreases(expression)			C6ORF48		C016340
CTD	increases(expression)			C9ORF72		C016340
CTD	increases(expression)			CABLES1		C016340
CTD	increases(expression)			CAPN9		C016340
CTD	increases(expression)			CARS		C016340
CTD	decreases(expression)			CCL2		C016340
CTD	increases(expression)			CCNA1		C016340
CTD	decreases(reaction)			CCND1		C016340
CTD	increases(expression)			CCND1		C016340
CTD	decreases(expression)			CCNE2		C016340
CTD	decreases(expression)			CD34		C016340
CTD	increases(expression)			CD55		C016340
CTD	decreases(expression)			CDCA8		C016340
CTD	increases(expression)			CDCP1		C016340
CTD	increases(expression)			CHAC2		C016340
CTD	decreases(expression)			CIRBP		C016340
CTD	increases(expression)			CPNE7		C016340
CTD	affects(localization)			CREB1		C016340
CTD	increases(activity)			CREB1		C016340
CTD	increases(phosphorylation)			CREB1		C016340
CTD	increases(activity)			CREBBP		C016340
CTD	increases(reaction)			CREBBP		C016340
CTD	decreases(reaction)			CREBBP		C016340
CTD	increases(expression)			CTSD		C016340
CTD	decreases(expression)			CX3CL1		C016340
CTD	decreases(reaction)			CYP19A1		C016340
CTD	increases(expression)			CYP19A1		C016340
CTD	decreases(activity)			CYP19A1		C016340
CTD	decreases(response to substance)			CYP19A1		C016340
CTD	increases(expression)			CYP1A2		C016340
CTD	increases(expression)			CYP2B6		C016340
CTD	increases(expression)			CYP2B6		C016340
CTD	decreases(reaction)			CYP3A4		C016340
CTD	increases(expression)			CYP3A4		C016340
CTD	increases(activity)			CYP3A4		C016340
CTD	increases(expression)			CYP3A4		C016340
CTD	increases(expression)			CYP3A4		C016340
CTD	increases(expression)			DHRS3		C016340
CTD	increases(expression)			DNER		C016340
CTD	increases(expression)			E2F7		C016340
CTD	increases(expression)			EIF2B4		C016340
CTD	increases(activity)			ELK1		C016340
CTD	increases(activity)			ERBB2		C016340
CTD	increases(expression)			ERCC3		C016340
CTD	decreases(expression)			ESR1		C016340
CTD	decreases(reaction)			ESR1		C016340
CTD	affects(cotreatment)			ESR1		C016340
CTD	affects(expression)			ESR1		C016340
CTD	affects(binding)			ESR1		C016340
CTD	increases(activity)			ESR1		C016340
CTD	affects(binding)			ESR1		C016340
CTD	increases(expression)			ESR1		C016340
CTD	affects(binding)			ESR1		C016340
CTD	decreases(reaction)			ESR1		C016340
CTD	decreases(expression)			ESR1		C016340
CTD	decreases(expression)			ESR1		C016340
CTD	increases(activity)			ESR1		C016340
CTD	affects(binding)			ESR2		C016340
CTD	increases(activity)			ESR2		C016340
CTD	decreases(expression)			ESR2		C016340
CTD	increases(activity)			ESR2		C016340
CTD	increases(expression)			ETNK2		C016340
CTD	decreases(expression)			FADS2		C016340
CTD	decreases(expression)			FAM107A		C016340
CTD	increases(expression)			FAM129A		C016340
CTD	increases(expression)			FASLG		C016340
CTD	increases(expression)			FBN2		C016340
CTD	decreases(expression)			FOLR1		C016340
CTD	increases(expression)			FOLR3		C016340
CTD	increases(expression)			FOSL1		C016340
CTD	increases(expression)			FOXD1		C016340
CTD	increases(expression)			G0S2		C016340
CTD	increases(expression)			GALNT4		C016340
CTD	decreases(expression)			GALR2		C016340
CTD	increases(expression)			GDPD5		C016340
CTD	increases(expression)			GPR142		C016340
CTD	decreases(expression)			GRAMD3		C016340
CTD	increases(expression)			GREM1		C016340
CTD	decreases(expression)			HAPLN3		C016340
CTD	increases(expression)			HES2		C016340
CTD	decreases(expression)			HIST1H2BD		C016340
CTD	increases(expression)			HIVEP1		C016340
CTD	decreases(expression)			HMGCS1		C016340
CTD	decreases(expression)			HMGN2		C016340
CTD	increases(expression)			HRK		C016340
CTD	decreases(expression)			HSPA2		C016340
CTD	decreases(expression)			IDI1		C016340
CTD	increases(expression)			IL24		C016340
CTD	increases(expression)			IL6R		C016340
CTD	increases(expression)			IMPDH2		C016340
CTD	increases(expression)			ITGA6		C016340
CTD	decreases(activity)			KCNA3		C016340
CTD	decreases(import)			KCNA3		C016340
CTD	decreases(activity)			KCNH2		C016340
CTD	decreases(import)			KCNH2		C016340
CTD	increases(expression)			KCTD20		C016340
CTD	decreases(expression)			KIF20A		C016340
CTD	decreases(expression)			KRT17		C016340
CTD	increases(expression)			LARP6		C016340
CTD	decreases(expression)			LDLR		C016340
CTD	decreases(expression)			LIPG		C016340
CTD	increases(expression)			LPPR2		C016340
CTD	decreases(expression)			LRRC17		C016340
CTD	decreases(expression)			LXN		C016340
CTD	increases(expression)			LYST		C016340
CTD	increases(expression)			MAGEA3		C016340
CTD	increases(expression)			MAK16		C016340
CTD	decreases(expression)			MANSC1		C016340
CTD	increases(activity)			MAP2K6		C016340
CTD	increases(reaction)			MAP2K6		C016340
CTD	decreases(reaction)			MAPK1		C016340
CTD	increases(phosphorylation)			MAPK1		C016340
CTD	increases(activity)			MAPK1		C016340
CTD	increases(reaction)			MAPK1		C016340
CTD	increases(phosphorylation)			MAPK1		C016340
CTD	decreases(expression)			MAPK13		C016340
CTD	increases(activity)			MAPK14		C016340
CTD	increases(reaction)			MAPK14		C016340
CTD	decreases(reaction)			MAPK3		C016340
CTD	increases(phosphorylation)			MAPK3		C016340
CTD	increases(phosphorylation)			MAPK3		C016340
CTD	decreases(reaction)			MAPK8		C016340
CTD	increases(phosphorylation)			MAPK8		C016340
CTD	decreases(reaction)			MAPK9		C016340
CTD	increases(phosphorylation)			MAPK9		C016340
CTD	decreases(expression)			MEOX1		C016340
CTD	increases(expression)			MET		C016340
CTD	decreases(expression)			MFGE8		C016340
CTD	increases(expression)			MFN2		C016340
CTD	increases(expression)			MLPH		C016340
CTD	increases(expression)			MRPS7		C016340
CTD	increases(expression)			MYCT1		C016340
CTD	affects(binding)			NCOA1		C016340
CTD	increases(reaction)			NCOA1		C016340
CTD	increases(expression)			NEIL2		C016340
CTD	increases(expression)			NME1		C016340
CTD	increases(activity)			NOTCH1		C016340
CTD	increases(reaction)			NOTCH1		C016340
CTD	increases(phosphorylation)			NOTCH1		C016340
CTD	decreases(reaction)			NOTCH1		C016340
CTD	increases(expression)			NPC1		C016340
CTD	affects(binding)			NR1I2		C016340
CTD	increases(activity)			NR1I2		C016340
CTD	increases(activity)			NR1I2		C016340
CTD	affects(binding)			NR1I3		C016340
CTD	increases(reaction)			NR1I3		C016340
CTD	increases(activity)			NR1I3		C016340
CTD	increases(expression)			OAF		C016340
CTD	increases(expression)			OLFM1		C016340
CTD	increases(expression)			OLFML3		C016340
CTD	increases(expression)			OSCAR		C016340
CTD	increases(expression)			PDCD7		C016340
CTD	decreases(expression)			PELI1		C016340
CTD	decreases(reaction)			PGR		C016340
CTD	increases(expression)			PGR		C016340
CTD	affects(binding)			PGR		C016340
CTD	decreases(reaction)			PGR		C016340
CTD	decreases(reaction)			PGR		C016340
CTD	increases(expression)			PGR		C016340
CTD	increases(expression)			PGR		C016340
CTD	increases(activity)			PI4KA		C016340
CTD	increases(expression)			PIM1		C016340
CTD	increases(expression)			PKM		C016340
CTD	decreases(expression)			PLA2G3		C016340
CTD	increases(activity)			PRKACA		C016340
CTD	increases(expression)			PRKAR2A		C016340
CTD	decreases(reaction)			PTGS2		C016340
CTD	increases(expression)			PTGS2		C016340
CTD	decreases(activity)			PTGS2		C016340
CTD	decreases(response to substance)			PTGS2		C016340
CTD	increases(abundance)			PTGS2		C016340
CTD	increases(expression)			RAB3IL1		C016340
CTD	decreases(expression)			RBPMS		C016340
CTD	decreases(expression)			RMI2		C016340
CTD	decreases(expression)			RRM2		C016340
CTD	increases(expression)			S1PR3		C016340
CTD	increases(expression)			SCAND2P		C016340
CTD	increases(expression)			SCGB1D2		C016340
CTD	increases(expression)			SERPINA3		C016340
CTD	increases(expression)			SERPINB5		C016340
CTD	increases(expression)			SESN2		C016340
CTD	increases(expression)			SF3B5		C016340
CTD	decreases(expression)			SGOL2		C016340
CTD	affects(binding)			SHBG		C016340
CTD	decreases(reaction)			SHBG		C016340
CTD	increases(expression)			SIAH2		C016340
CTD	decreases(expression)			SLC10A1		C016340
CTD	increases(expression)			SLC1A5		C016340
CTD	decreases(expression)			SLC22A1		C016340
CTD	increases(expression)			SLC31A1		C016340
CTD	increases(expression)			SLC35F5		C016340
CTD	increases(expression)			SLC38A1		C016340
CTD	increases(expression)			SLC7A5		C016340
CTD	increases(expression)			SLCO2A1		C016340
CTD	decreases(expression)			SPC25		C016340
CTD	decreases(expression)			SQLE		C016340
CTD	increases(expression)			STC2		C016340
CTD	increases(expression)			TFEC		C016340
CTD	decreases(reaction)			TFF1		C016340
CTD	increases(expression)			TFF1		C016340
CTD	decreases(reaction)			TFF1		C016340
CTD	increases(expression)			TFF1		C016340
CTD	increases(expression)			TFF1		C016340
CTD	decreases(expression)			TFF2		C016340
CTD	increases(expression)			TGFA		C016340
CTD	decreases(expression)			TGFB2		C016340
CTD	increases(expression)			THBD		C016340
CTD	increases(expression)			THBS1		C016340
CTD	decreases(expression)			TMED4		C016340
CTD	increases(expression)			TNFRSF14		C016340
CTD	decreases(expression)			TSC22D1		C016340
CTD	increases(expression)			TSKU		C016340
CTD	increases(expression)			TSPAN10		C016340
CTD	decreases(expression)			TSPAN12		C016340
CTD	decreases(expression)			TXNIP		C016340
CTD	decreases(expression)			VCPKMT		C016340
CTD	increases(expression)			VEGFA		C016340
CTD	increases(expression)			ZKSCAN2		C016340
CTD	increases(expression)			ZMYM3		C016340
PubChem	Potency	uM	22.387	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.935	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.696	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.132	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.443	ESR1	-	GI(Protien) :
PubChem	Potency	uM	1.585	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.354	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.372	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	5.725	ESR1	-	GI(Protien) :
PubChem	Potency	uM	61.131	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	74.978	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	18.103	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	22.387	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.811	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	20.312	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	22.020	NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	22387.200	ALDH1A1	-	Target : CHEMBL3577

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